BIONABU® · VERA DEVIATE™
One source of truth.
Every deviation.
Inspection-ready.

Protocol Deviation Management Software

Deviation tracking, CAPA oversight and quality review — consolidated from EDC and site logs into one governed record.

The single, verifiable record of what happened, when, and who caught it — captured early, reviewed by role, and traceable to closure under 21 CFR Part 11.

THE PROBLEM

Protocol deviations live in a dozen Excel logs

Every site keeps its own log. CRAs, CRO operations and the sponsor reconcile them by hand against the EDC export — weekly, biweekly, quarterly. It's slow, error-prone, and there is no single audit trail to put in front of an inspector.

Per-site Excel logs

Each site maintains a separate spreadsheet, in its own format, with no shared controlled vocabulary.

Manual reconciliation

Teams aggregate and cross-check logs against the EDC export by hand, on three different cadences.

No single audit trail

Status changes sit in meeting minutes. The data can't be queried without manual compilation.

WHAT IT IS

One governed record for every protocol deviation

Vera Deviate takes in your EDC export and your existing per-site logs, applies the review workflow, holds a tamper-evident audit trail, and serves every report and query live. Every deviation records who caught it — the site, the CRA, the sponsor, or the EDC itself — so the source of each finding is part of the record, not someone's memory. The spreadsheets and the manual reconciliation are retired; Vera becomes the single system of record.

EDC & manual intake

Ingests the EDC audit-trail export, takes in existing per-site Excel logs, and lets CRAs log deviations directly — all into one record, no re-keying.

Role-based review

Site, CRA, CRO operations and sponsor each see exactly their scope, enforced server-side.

Tamper-evident audit trail

Every create, edit, status change and import is written to an append-only log with actor, reason and before/after values.

Live reports

Meeting agendas, escalation views and the quarterly summary generate on demand — not by hand.

HOW IT WORKS

Four review stages, one system

Vera Deviate supports the full deviation-management workflow natively — no switching between Excel, the EDC and the issue tracker.

01
Site & CRA review

The site logs the deviation in the EDC; Vera ingests it on import. The CRA can also log directly when a site has no EDC access.

02
Weekly operations

The Vera dashboard is the meeting agenda — open deviations, escalations and ageing. Changes are captured live in the audit trail.

03
CRO / sponsor review

Escalated deviations surface alongside their CAPA reference, linked to your issue/CAPA tool. Reviewed by role on a biweekly cadence.

04
Quarterly data review

The summary report — counts by site, country, category, grade, status and ageing, with quarter-on-quarter trend — generates on demand.

THE DIFFERENCE

Manual reconciliation vs. Vera Deviate

Without
  • One Excel log per site, in different formats
  • Hand reconciliation against the EDC, three cadences
  • Status history scattered across meeting minutes
  • Inspection prep is a manual scramble
With Vera Deviate
  • One governed record across all sites
  • EDC ingested automatically; no re-keying
  • Tamper-evident audit trail, every change captured
  • Reports — and inspection readiness — on demand
COMPLIANCE

Built for 21 CFR Part 11 and GDPR

Compliance is designed in, not bolted on — so the record holds up when an inspector asks to see it.

Tamper-evident audit trail

Append-only log; every privileged action carries a typed reason and timestamp in UTC.

Electronic signatures

Close-out, reopen and void require e-signature with re-authentication.

Role-based access

Site-scoped data segregation enforced server-side; participant identifiers minimised from the sponsor view.

EU data residency

All data hosted in the EU. Data-processing agreement provided to sponsors.

VERA DEVIATE™ v1.0 · GCP · 21 CFR PART 11 · GDPR · EU-HOSTED
TRACTION

In production, not in a slide deck

Tier-1 CRO
Running in production on a live multi-country observational study
Built by a former senior CPM
Designed from inside the protocol-deviation workflow, not from outside it
21 CFR Part 11 · GDPR
Audit trail, e-signatures and EU residency from day one

Reference deployment and study details available under NDA.

ONE CLOSED LOOP

Part of the Bionabu system

Vera Deviate is the downstream layer. Upstream, PrepStoriesAI prepares the patient; in the middle, Vera Content governs what they read. Same standard, end to end.

Book a walkthrough.

We'll map one of your studies to Vera Deviate and tell you whether it fits. If it doesn't, we'll tell you that too.

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